Splenda Potentially Toxic to Humans

There was an interesting study released this week from Duke University. It seems that sucralose, the artificial sweetener that is listed as GRAS (Generally Recognized as Safe) by the FDA causes serious adverse effects in rats in the 12 week study. The adverse effects were seen in rats given 1.1mg/kg of sucralose, where the FDA acceptable limit in humans is 5mg/kg. Therefore adverse effects were seen in amounts below the FDA acceptable limits.
We know that good gut bacteria is important for health, there have been enough studies showing the importance of taking a probiotic or eating cultured foods. According to this study if we extrapolate the results seen in rats to humans if someone uses Splenda as allowed by the FDA they very well may reduce their beneficial bacteria by 50%! I know of many people that complained of digestive issues who were heavy Splenda consumers. It will also increase body weight, alter liver cytochrome detoxification and increase pathogenic gut bacteria.
A one time use probably isn’t going to make a difference, but using it several times a week sure can cause adverse effects. Two cups of coffee a day can surely lead to digestive issues. What is also interesting is that when Splenda was tested by Johnson & Johnson to get approval for use by humans it was found to have potential adverse health effects, yet it was still approved!
The people who really shouldn’t been on Splenda are patients undergoing chemo or patients on drugs with a narrow therapeutic window because of the alteration in liver detoxification gene expression. It can cause a deleterious alteration in how long the drug remains in a persons body. Bottom line is don’t use artificial food substitutes! I don’t care what the FDA or Big Pharma companies tell us, if it is artificial our bodies for the most part do not want it.
If one isn’t a diabetic then using whole sugar, date sugar, honey (unheated) are better options. The closer to a whole food the better. Some people love the agave syrup, but there has been some questions raised about its safety (see Russ Block’s blog on Mercola.com). Stevia tastes a bit strange to me. Another way to get sugar and the best way is to chew, chew, chew your carbohydrates. The salivary glands contain copious amounts of amylase to break down carbohydrates into simple sugars. That is why if you chew rice for a while it keeps getting sweeter and sweeter as the polysaccharides are breaking down into shorter sugar chains and eventually a simple monosaccharide (sugar).

In Health
George Mandler
Acupuncture, Nutrition, Herbal Medicine
Cambridge, MA

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